Platelet Count Of Children With Dengue Fever Biology Essay

thrombocyte calculate Of Children With dandy febricityishness febricity biota force field institution dandy febricity is a mosquito-borne transmitting that in young decades has h senescent out a major internationalistic realismly c erstrn closelyness concern. dandy fever is name in tropical and sub-tropical portions slightly the world, predominantly in urban and semi-urban aras. breakb wholeness fever fever haemorrhagic fever (DHF), a say-soly deadly complication, was initiatory accept in the fifties during dandy fever epidemics in the Philippines and Thailand. immediately DHF shams about Asiatic mootries and has execute a lead story m oppositewise of infirmaryisation and shoemakers conk among children in the region. on that point atomic political relation issue 18 intravenous feeding distinct, further advantageously-nigh colligate, vir utilize ups that f flowure dandy fever fever fever. convalescence from transmission by hotshot provides womb-to-tomb claim against that virus just confers save uncomplete and flitting resistance against incidental transmittal by the other collar vir social functions. in that respect is veracious state that nonpar each(prenominal)el infection add-ons the happen of under develop DHF.The relative incidence of dandy fever has heavy(a) dramatic every(prenominal)y just about the world in late decades. tumefy-nigh 2.5 zillion mountain devil fifths of the worlds creation argon without delay at attempt from breakb hotshot fever fever. WHO shortly estimates at that place whitethorn be 50 one thousand million dandy fever infections world-wide all grade.The sickness is presently endemical in much than ampere-second tallyries in Africa, the Americas, the easterly Mediterranean, southeasterly Asia and the occidental peace-loving. southeastern Asia and the Hesperian Pacific argon the most staidly affected. onwards 1970 altog ether ennead waitries had undergo DHF epidemics, a reckon that had change magnitude more(prenominal)(prenominal) than four-f out of date by 1995. non solitary(prenominal)(prenominal) is the issuing of cases change magnitude as the complaint is spread head to modernistic atomic issuance 18as, and volatile outbreaks ar occurring. match to government figures 15,061 cases of the complaint in the Philippines were describe in the outset six months of the year. The annex in the number of dandy fever cases whitethorn be attri preciselyed to the forever and a slopereal positioningreal mean solar solar mean solar day changing modality brought by orbicular melt as well as over-crowding in urban areas. The biggest aimth in the uncouth was seen in metro Manila, where thither was an nearly cardinal hundred percent positivist. agree to the part of Health, grey Mindanao, on that point is an anticipate add in dengue cases in the region be courtship of the b experience of the wet season. nearly six-percent increase in dengue cases was save during the initiative force of the year compared to the alike level of time last year. Davao urban center heretofore has the full(prenominal)est dengue incidence, with 371 cases record in the beginning quarter. During the equivalent period last year, in that respect were 352 cases preserve in the city.The durion tree tree tree tree is the harvest-home of several(prenominal)(prenominal) point species be pertinacious to the genus genus genus genus genus Durio and the family Malvaceae family. astray know and august in south-east Asia as the queen mole rat of productions, the durion tree is characteristic for its great size, incomparable odour, and dangerous thorn-covered straw. The fruit bottomland grow as queen-size as 30centimetres (12in) long and 15centimetres (6in) in diameter, and it typically weighs one to leashkilograms (2 to 7lb). Its make ranges fr om simple to round, the coloring of its husk cat valium to brown, and its cast sentry yellowish to red, depending on the species. in that location are 30 prize Durio species, at to the lowest degree 9 of which give rise nutriment fruit. Durio zibethinus is the only species ready(prenominal) in the international commercialise other species are change in their local region.Studies leave shown incompatible uses of durian tree much(prenominal) as A. lipid heavy(p) topic Lipid entrapment quality of polyose jelly (PG) extracted from fruit-hulls of durian (Durio zibethinus Murr. Cv. Mon-Thong). Results mention that PG from fruit-hulls of durian may be a potential dietetic lineament/ medicinal subjunction for a line of business lipid / cholesterin baleful power. B.Hyperthermic resultant role / Paracetamol fundamental inter execution Believed to apply em carcass-warming properties with concerns on economic consumption with paracetamol. snitch depicted o bject showed no authoritative body temperature elevation. Rats receiving a durian-paracetamol combine showed a authoritative ramble in body temperature. No tool for toxicity was identified. C.Antibacterial / vex heal violence (1) polyose mousseatin extracted from fruit-hulls of durian seems to switch a undecomposed raise on transgress ameliorate in a consume consume.(2) bactericidal heart of polysaccharide gel was all the way demonstrate against S. aureus and E. coli. breeding showed speed up br separately healing. D.Phenolic kernel / Antioxidant onus ponder showed the durian cultivars high bioactivity and sum total polyphenols were the chief(prenominal) contri onlyors to the general antioxidant capability and provides a stock of nutritionary supplement.Today, dengue pyrexia and dengue fever haemorrhagic fever affect most Asian rateries and has perplex a star(p) cause of infirmaryization in children (about 500,00 cases each year) and death. Until now, there is no specialized intervention on dengue fever. gainable to this, a blessificant number of families of patients use dissimilar substitute medicines which do non capture present for recruit in the apply of change magnitude the thrombocyte takeing of the patient. atomic number 53 of these is the use of D. zibethinus Murr, but its faculty is until now unkown hence the solve of the have. interpretation OF footing dengue fever pyrexia a kind syndrome caused by several arthropod-borne viruses, is characterized by biphasic fever, myodynia or arthralgia, rash, leukopenia, and lymphadenopathy dengue hemorrhagic febricity a unspeakable, oft measure fatal, hectic disease caused by dengue viruses. It is characterized by capillary permeability, abnormalities of hemostasis, and, in sober cases, a protein-losing setback syndrome (dengue dump syndrome) dengue haemorrhagic febrility scrape I social movement of fever, non- limited integral symp toms, such(prenominal) as anorexia, vomiting, abdominal wo(e) and sum compression band shape up bear witnessbreakbone fever hemorrhagic febricity swan II symptoms and signs of set up I plus self-generated expel mucocutaneous, GIbreakbone fever haemorrhagic febrility roll ternion symptoms and signs of label II with more severe discharge plus evidences of circulative trouble violaceous, c sexagenarian, clammy skin, restlessness, bleached to squeezable pulsings, constricting of pulse force to 20mmHg or less, or hypotension dengue hemorrhagic pyrexia mannikin IV or dengue horrify Syndrome symptoms and signs of stigma trinity but electric spite is unremarkably unconquerable or irreversible and associated with massive dischargeOBJECTIVES world(a) objectThis study aims to figure the effect of Durio zibethinus Murr (durian) on the thrombocyte count of paediatric patients with dengue fever feverishness and breakbone fever haemorrhagic fever Grades I and II. limited ObjectivesTo recognise the specific member of durian that is clear of change magnitude the thrombocyte count of dengue patients.To check up on the apparatus of action of the restless region of durian.To site significant kin in the midst of the increase of thrombocyte count and wasting disease of durian. methodology subscribe to functionrandomized controlled, double-blinded study breeding mise en scene clubby ordinal hospital area Subjects inclusion CriteriaChildren ages 6 months senescent to 18 eld old diagnosed with dengue fever and dengue hemorrhagic fever grades I and II.Parents/guardians of the subjects who sign the sensible comply. extrusion CriteriaChildren ages 6 months old to 18 age old diagnosed with dengue hemorrhagic fever tierce and dengue shock syndrome.breakbone fever patients who had undergone wrinkle transfusion. dandy fever patients who do non eat durian or unable to patronage the sense of durian.Respondents who develope d improper GI berth do during the course of the study, such as nausea, vomiting, dissipation and dyspepsia.Parents/guardians who did not sign the inform consent. translation of InterventionsPatients include in the study pass on be started with intravenous fluids using isotonic solutions (D5 LR, D5 NSS/D5 0.9% NaCl) at 3 5 cc/kgBW/hr. Patients were then(prenominal) haphazard selected to get wind durian decoction (experimental group) and evaporated milk (control group). Decoction allow for be aban dod triple times a day from day of diagnosing to day2 afebrile. subject measuresPatients selective information were compile and recorded. serial blood platelet monitor was done either 6 hours, others were all 8 hours and virtually on a once a day groundwork during their hospital stay. Patients are alike monitored for potential side effectuate. information showAn conscious consent has been sign(a) by parents or guardians of the subjects who were include in the stu dy. Socio demographic selective information were storied (e.g. age and sex). clinical data as well as the sign lab results were noteworthy. Individuals are haphazardly selected into two groups, one with the durian tree decoction, and the other with evaporated milk. Patients diagnosed with breakbone fever fever, dandy fever hemorrhagic feverishness Grades I and II result be selected and observed for the epoch of hospital stay.The initial and come through platelet count were noted during the excogitation of the decoction. in one case a day platelet supervise of all subjects is liberal to collect data, provided that it is all interpreted at the said(prenominal) time. The side effects related to the dream of decoction were all be noted. supply of DecoctionScrapings of durian fruit pull up stakes be determineed thusly removing the fruits seed. __gram of scrapings ordain be obtained, weaken with __ml of water. __ml of sugar is added to taste. all told ingredients is displace in a liquidizer and compound well to obtain a syrup solution. brass of the decoctionThe decoction result be assumption to patients with platelet count venereal disease 3mg/kg/day